The Effects of Local Spatial Structure on Epidemiological Invasions (1999)

Keeling, M.  Proc. Roy. Soc. Lond. B  266 859-869

ABSTRACT

Predicting the likely success of invasions is vitally important in ecology and especially epidemiology. Whether an organism can successfully invade and persist in the short term is highly dependent upon the spatial correlations that develop in the early stages of invasion. By modelling the correlations between individuals we are to understand the role of spatial heterogeneity in invasion dynamics without the need for large-scale computer simulations. Here, a natural methodology is developed for modelling the behaviour of individuals in a fixed network. This formulation is applied to the spread of a disease through a structured network to determine invasion thresholds and some statistical properties of a single epidemic.



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